CYANOCOBALAMIN (VITAMIN B12)
Shape and Properties
This product is a crimson crystal or crystalline powder, odourless, tasteless and has strong moisture-inducing properties. Slightly soluble in water or ethanol, insoluble in chloroform or ether. Heat-resistant, but it can be ineffective when exposed to oxidising or reducing substances, heavy metal salts and strong acids and strong alkalis.
Chemical Structure
Vitamin B12 is an equioctaphedral compound containing cobalt ions. Its central structure is a flat corrin ring composed of four pyrroles connected. The molecules of vitamin B12 are roughly composed of 3 parts: a gourin ring chylated by four N atoms and central cobalt ions; 5,6-dimethylbenzimidazole connected to N-7 atoms and cobalt ions as vitamin B 12 molecules of low-level ligands. In addition, DMBI is also connected to aminopropanol through phosphate groups, and aminopropanol is covalently connected to the propionic acid side chain on pyrrole D; adenosyl group or methyl group It is connected with cobalt ions to form the upper ligand of vitamin B12 molecules.
Physiological Function
Vitamin B12 deficiency can lead to peripheral neuritis. The early manifestations of vitamin B12 deficiency in children are abnormal mood, sluggish expression, slow reaction, and finally lead to anaemia. Promote the development and maturity of red blood cells. Methylpropandiyl coenzyme A is converted into succinoyl coenzyme A and participates in the tricarboxylic acid cycle, in which succinyl coenzyme A is related to the synthesis of heme. Vitamin B12 also participates in the synthesis of deoxynucleic acid (DNA), the metabolism of fat, carbohydrates and protein, and increases the synthesis of nucleic acids and proteins.
