Creatine
Introduction
Creatine, also known as α-methylmethyl acetic acid, is a natural nutrient that exists in the human body. It can also be synthesised from arginine, glycine and methionine in the liver, kidney and pancreas: under the catalysis of renal arginine glycine trans-benzyme, the benzyl group of arginine is transferred to glycine. On the amino group, acetic acid is produced. Then the liver is catalysed by methyltransferase of acetic acid, and the methyl of S-adenosine methionine is transferred to acetic acid to produce creatine.
Chemical properties
Prismatic crystals . The melting point is 303℃ and the relative density is 1.33. Soluble in boiling water and 98% acetic acid, slightly soluble in ethanol, insoluble in ether and butyric acid. In aqueous solution, it is obtained with mercury acetate at room temperature to obtain methyl acethyde, and finally methylamine and oxalic acid are formed.
USE
Creatine has the basic functions of increasing the water content of muscle cells, helping muscle cells store energy, and increasing the synthesis of protein. Among them, artificially synthesised creatine can be used to promote the adaptation of bone muscles to strenuous exercise and fight the fatigue of weak individuals. It can also be used to prepare drugs to treat heart disease and respiratory insufficiency; prepare pharmaceutical preparations containing human growth hormone; and can be used to compound a new healthy food, which has the effect of anti-ageing and physical recovery.
